WWE WrestleMania 41 Picks, Odds, and Preview

The biggest show on the wrestling calendar is set for Las Vegas across the weekend of April 19 and 20, 2025.

WrestleMania 41 will take place at Allegiant Stadium in Sin City, with the headline bout seeing John Cena go in search of a record-breaking 17th world title against Cody Rhodes.

WrestleMania 41 Event Information

Cody Rhodes vs. John Cena Odds & Pick

The standout match at WrestleMania 41 this year will see Cody Rhodes defend his Undisputed WWE Championship against 16-time world champion John Cena.

Rhodes has been the champion since ending Roman Reigns’ historic reign at Mania last year, successfully defending the title against the likes of Kevin Owens, Solo Sikoa, and AJ Styles. Cena secured his spot in the Mania main event after winning the Elimination Chamber, but that only tells half of the story.

One of the most shocking events in WWE history occurred following his win, as Cena aligned with The Rock, turning heel for the first time in his 25-year career. Since then, Cena has vowed to make fans miserable by retiring with the championship, and the first part of that promise could be secured in Las Vegas.

Tiffany Stratton vs. Charlotte Flair Odds & Pick

The SmackDown Women’s Championship will also be defended at WrestleMania in Las Vegas, as Tiffany Stratton defends the gold against Charlotte Flair.

Stratton won the title after successfully cashing in on Nia Jax, and she has since turned face after becoming the choice of fans. There is no surprise to see Flair inserted back into the championship picture, and she earned her spot in this match after winning the Royal Rumble.

Flair is the current favorite, but it would make limited sense for the veteran to bury a rising name in the women’s division, meaning that we remain Team Stratton.

Jey Uso vs. Gunther Odds & Pick

Jey Uso was the shock winner of the men’s Royal Rumble this year, and he will challenge Gunther for the World Heavyweight Championship.

Uso lost to Gunther at Saturday Night’s Main Event in January, before winning the Rumble seven days later. The prolonged rivalry between the stars is beginning to tire with fans, with Raw typically following a similar pattern week-by-week.

One of the big shocks of the weekend could come in this match, as we could see Gunther retaining the title.

Roman Reigns vs. Seth Rollins vs. CM Punk Odds & Pick

The likely main event on night one of Mania in Vegas will see a heated rivalry involving three of the top WWE stars come to a head. CM Punk’s return to the company led to an immediate confrontation with Seth Rollins, with the Straight Edge Superstar beating Rollins on the Raw Netflix debut.

However, the rivalry intensified at the Royal Rumble, with Roman Reigns and Rollins being eliminated by Punk, before the Head of the Table returned on Raw a few weeks ago to cost Punk in a steel cage match against Rollins.

Paul Heyman’s part in this match could be the likely angle that could ultimately decide the outcome. His affiliation with Reigns has been a trademark in WWE across recent years, but it shouldn’t be lost on fans that Punk is a Heyman Guy.

But, a major swerve could see Heyman align with Rollins, giving the former Shield member a major win at Mania over his two biggest rivals.

Other WrestleMania 41 Picks